IDENTIFICATION OF A BROAD SARBECOVIRUS NEUTRALIZING ANTIBODY TARGETING A CONSERVED EPITOPE ON THE RECEPTOR-BINDING DOMAIN

Identification of a broad sarbecovirus neutralizing antibody targeting a conserved epitope on the receptor-binding domain

Summary: Omicron, as the emerging variant with enhanced vaccine tolerance, has sharply disrupted most therapeutic antibodies.Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) belongs to the subgenus Sarbecovirus, CHOCOLATE BROWNIE BAR members of which share high sequence similarity.Herein, we report one sarbecovirus antibody, 5817, which

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Constructing a systems psychodynamic wellness model

Orientation: The researchers constructed a Systems Psychodynamic Wellness Model (SPWM) by merging theory and concepts from systems psychodynamics and positive psychology.They then refined the model for application in organisations during a Listening Post (LP) that comprised experienced subject experts.Research purpose: The purpose of the research w

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